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. 2021 Jun 14;21:699. doi: 10.1186/s12885-021-08401-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Comparison of cumulative HCC recurrence (%) by sex (A). Cumulative HCC recurrence is significantly higher in males than in females, according to the log-rank test (p = 0.017). Comparison of cumulative HCC recurrence (%) by sustained virological response (SVR) achievement (B). Cumulative HCC recurrence is significantly higher in the ‘no SVR’ group than in the group with SVR according to the log-rank test (p = 0.003). Comparison of cumulative HCC recurrence (%) between the group with more than two past HCC treatments and the group with only one HCC treatment (C). Cumulative HCC recurrence is significantly higher in the group with more than two past HCC treatments according to the log-rank test (p = 0.001). Cumulative recurrence (%) of HCC according to the score combining sex, SVR achievement, and number of past HCC treatments (D). Study patients are grouped based on these scores: 0 points, low-risk group (n = 39); 1 or 2 points, intermediate-risk group (n = 88); and 3 points, high-risk group (n = 72). Cumulative HCC recurrence increases significantly with higher scores (p < 0.001)