Table 1. Cheminformatics Analysis (ROCS).
| compound | reference compound | shape Tanimoto | color Tanimoto | Tanimoto combination |
|---|---|---|---|---|
| navitoclax | navitoclax | 1 | 1 | 2 |
| navitoclax | A-1155463 | 0.222 | 0.119 | 0.341 |
| navitoclax | A-1331852 | 0.389 | 0.108 | 0.497 |
| A-1331852 | A-1155463 | 0.378 | 0.169 | 0.546 |
| A-1293102 | A-1155463 | 0.389 | 0.091 | 0.480 |
| A-1293102 | A-1331852 | 0.344 | 0.122 | 0.467 |
| A-1293102 | navitoclax | 0.461 | 0.442 | 0.904 |