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. 2021 May 7;12(6):991–995. doi: 10.1021/acsmedchemlett.1c00135

Table 2. XTT IC50 of Selected Picolinamides Analogues with HeLa Cells.

  IC50 (μg·mL–1)
4 79.9 ± 1.0
5 179.3 ± 3.6a
87 95.2 ± 1.0
89 170.2 ± 2.5
90 NT at 64b
92 NT at 256b
93 NT at 64b
94 40.1 ± 1.6
97 135 ± 8.6
98 114.8 ± 2.2
99 37.0 ± 1.0
106 105.9 ± 2.1
107 88.0 ± 2.3
108 93.3 ± 1.7
109 77.4 ± 2.3
110 91.6 ± 1.3
114 53.3 ± 3.6
116 NT at 128b
118 79.9 ± 6.3
119 123.6 ± 3.3
a

Reported previously21 and included here for comparison.

b

NT, no detectable toxicity at the specified concentration.