Table 2. XTT IC50 of Selected Picolinamides Analogues with HeLa Cells.
| IC50 (μg·mL–1) | |
|---|---|
| 4 | 79.9 ± 1.0 |
| 5 | 179.3 ± 3.6a |
| 87 | 95.2 ± 1.0 |
| 89 | 170.2 ± 2.5 |
| 90 | NT at 64b |
| 92 | NT at 256b |
| 93 | NT at 64b |
| 94 | 40.1 ± 1.6 |
| 97 | 135 ± 8.6 |
| 98 | 114.8 ± 2.2 |
| 99 | 37.0 ± 1.0 |
| 106 | 105.9 ± 2.1 |
| 107 | 88.0 ± 2.3 |
| 108 | 93.3 ± 1.7 |
| 109 | 77.4 ± 2.3 |
| 110 | 91.6 ± 1.3 |
| 114 | 53.3 ± 3.6 |
| 116 | NT at 128b |
| 118 | 79.9 ± 6.3 |
| 119 | 123.6 ± 3.3 |
Reported previously21 and included here for comparison.
NT, no detectable toxicity at the specified concentration.