Table 3. MIC Values (μg·mL^–1) for MTZ, VAN, FDX, and Compounds 4, 5, 87, and 108 against Major Gut Bacteria.

	MTZ	VAN	FDX	4	5a	87	108
C. difficile ATCC43255	0.25	0.5	0.0625	0.25	0.125	0.125	1
Bacteroides fragilisa	1	16	>32	1	4	4	8
Bifidobacterium longumb	1	0.25	<0.01	>16	16	>16	16
Corynebacterium spp.c	>32	0.5	<0.0625	0.5	8	16	>16
Fusobacterium nucleatumid	2	0.25	<0.0625	8	4	8	8
Lactobacillus reuterie	>32	>32	>32	8	4	4	4
Lactobacillus gasserif	>32	1	2	>16	>16	>16	>16
Veillonella sp.g	2	>32	8	4	16	16	16
Eubacterium sp.h	1	2	16	>16	16	8	8

^aStrain HM-709, a Gram-negative, anaerobic bacterium that is commensal and critical to host immunity and a minor component of the human gut microflora (<1%).

^bStrain HM-846, an anaerobic, nonsporulating Gram-positive bacterium commonly found in the normal human intestinal microflora isolated from human feces.

^cStrain HM-784, an aerobic or facultatively anaerobic Gram-positive bacterium that occurs in the mucosa and normal skin flora of humans and animals.

^dStrain HM-992, an anaerobic, nonsporulating Gram-negative bacterium commonly found in the gastrointestinal tract.

^eStrain HM-102, an anaerobic Gram-positive bacterium commonly found in the normal human gastrointestinal tract, and used frequently as a probiotic to maintain the balance of gut microbial flora.

^fStrain HM-644, a facultative, anaerobic Gram-positive bacterium commonly found in the normal human gastrointestinal tract, used frequently in yogurt production as a probiotic to suppress Helicobacter pylori infections.

^gStrain HM-49, a nonsporulating Gram-negative bacterium commonly found in the intestinal tract of humans and animals.

^hStrain HM-178, an anaerobic, nonsporulating Gram-positive bacterium commonly found in the gastrointestinal flora of humans and animals.