Table 4. Drug Concentrations in Fecal Samples of Selected Compounds.
| MIC, μg·mL–1a | selectivityb | dose, mg·kg–1 | μg g–1 feces | conc. feces/MIC | |
|---|---|---|---|---|---|
| 4 | 0.25 | 1 | 20 | 2.8 | 11 |
| 5c | 0.125 | 128 | 20 | 13 | 108 |
| 87 | 0.125 | 1024 | 10 | 0.79 | 6.6 |
| 107 | 1 | ≥256 | 20 | 2.4 | 2.4 |
| 108 | 1 | 64 | 20 | 49 | 49 |
| 116 | 0.50 | 128 | 20 | 3.7 | 7.4 |
C. difficile strain, ATCC 43255, ribotype 087.
Selectivity is defined as MICMRSA/MICC. difficile.
Reported previously; included for ease of comparison.