Skip to main content
. 2021 May 24;12(6):955–960. doi: 10.1021/acsmedchemlett.1c00094

Table 1. Exploration of [5,5]- and [5,6]-Bicyclic Triazolotriazine Replacements.

graphic file with name ml1c00094_0005.jpg

graphic file with name ml1c00094_0006.jpg

a

Inhibition of cMet kinase activity (Ki) was determinated by standard radiometric assay.

b

The cell IC50 was determinated using MKN gastric carcinoma.

c

LipE value calculated from c-Met pKi.