Fig. 2.

RHOX10-regulated genes in fetal germ cells. (A) Principal component analysis plot of the RNA-seq datasets from quadruplicate testicular germ cell samples obtained from E16.5 Rhox10-null; Oct4-eGFP^+/+ (KO) and Oct4-eGFP^+/+ (WT) mice. (B) Heatmap of DEGs identified from the analysis of the samples in A (the data from each biological replicate are shown). Selected signaling pathways enriched in DEGs down- and up-regulated in Rhox10-null germ cells are shown in Upper and Lower, respectively. (C and D) STRING analysis of DEGs defined in B.