Table 2.
Logistic regression and ROC curve analysis.
| Logistic Regression | ldESI-SOZ | ||
|---|---|---|---|
| Predictor of outcome | Adjusted Odds Ratio | 95% C.I. | p-value |
| Dres [mm] | 0.91 | 0.83–0.99 | 0.04 |
| Gender (female vs male) | 2.14 | 0.27–17.05 | 0.47 |
| Duration of epilepsy to surgery (years) | 0.96 | 0.79–1.16 | 0.7 |
| Seizure frequency (md vs dw) | 0.91 | 0.11–7.56 | 0.93 |
| Seizure frequency (md vs wm) | 3.73 | 0.24–57.29 | 0.34 |
| Resection volume (cm3) | 1.00 | 0.96–1.04 | 0.82 |
| MRI lesion (l vs nl) | 0.32 | 0.04–2.7 | 0.29 |
| Type of resection (T vs extraT) | 1.57 | 0.29–9.32 | 0.62 |
| ROC curve analysis | Resected* | Not Resected* |
|---|---|---|
| SF (%) | 12 (57) | 9 (43) |
| NSF (%) | 2 (14) | 12 (86) |
| AUC (95% C.I.) * | 0.71 | (0.53–0.88) |
| NPV (95% C.I.) | 57.1 | (34–92.5) |
| PPV (95% C.I.) | 85.7 | (57.2–94.2) |
| Specificity (95% C.I.) | 85.7 | (57.2–98.2) |
| Sensitivity (95% C.I.) | 57.1 | (34–78.2) |
| Accuracy (95% C.I.) | 68.6 | (50.7–83.5) |
| p-value | 0.01 |
Dres = Distance of ldESI-SOZ from surgical resection (mm); Md = multiple daily; dw = daily-weekly; wm = weekly-monthly;
T = temporal; extraT = extra-Temporal; l = lesional; nl = non-lesional; NPV = negative predictive value; PPV = positive predictive value;
C.I. = Confidence Interval; MRI = Magnetic Resonance Imaging; ROC = Receiver operating characteristic; SF = seizure-free;
NSF = non seizure-free; AUC = area under the curve; NPV = Negative Predictive Value; PPV = Positive Predictive Value.
*
Resected above optimal cut-off (60%).