Fig 6. Discordant uptake of [11C]acetate and [18F]florbetapir in the lungs.
Early (2–6 minutes after injection of radiotracer) axial and coronal images in one subject showed minimal lung uptake of [11C]acetate (Fig 6a) despite intense lung uptake of [18F]florbetapir (Fig 6b). We propose that this discordant finding combined with high [18F]florbetapir Vs, the distribution volume of [18F]florbetapir specific binding in the lungs derived from compartmental modelling, suggests pulmonary AL amyloidosis