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Determination of pubertal onset and estrous cycle in miR-29a/b1 KO females. (A) Pubertal onset was determined by vaginal opening in wild-type and miR-29a/b1 KO mice (n=8). (B) Body weight of mice at the time of puberty onset (wild-type: 14.18 ± 0.5660, miR-29a/b1 KO: 8.74 ± 0.5202, p=0.0001, n=5). (C) Estrous cycle quantitative measurements on wild-type and miR-29a/b1KO females (1: p=0.9133, 2-4: p<0.0001). ***p < 0.001, ****p < 0.0001.
