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. 2021 May 31;12:698275. doi: 10.3389/fphar.2021.698275

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Copyright © 2021 Feng, Feng, Zhang, Li and Yao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Matrix stiffness induces YAP activity. (A) Representative images of YAP activation along different matrix stiffness. Nuclei were stained with DAPI. Scale bar is 20 um. (B) Statistical analysis of YAP nuclei/cytoplasm ratio along different matrix stiffness.