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. 2021 May 31;12:695315. doi: 10.3389/fphar.2021.695315

TABLE 2.

Comparison of sociodemographic, clinical and pharmacological variables with types of dementia in a group of patients in Colombia, 2019.

Variables Alzheimer’s disease Unspecified dementias Vascular dementia Dementia in Parkinson’s disease Other dementias
n = 8,711 % n = 1767 % n = 657 % n = 201 % n = 36 %
Woman 5,945 68.2 1,151 65.1 375 57.1 87 43.3 15 41.7
Age (mean; SD) 80.7 ± 9.5 80.5 ± 10.1 80.9 ± 9.7 77.7 ± 9.5 68.4 ± 9.6
Geographic regions
Pacific region 2045 23.2 599 33.9 299 45.5 75 37.3 11 30.6
Bogotá-cundinamarca region 2,304 26.4 523 29.6 110 16.7 34 16.9 11 30.6
The caribbean region 2,332 26.8 297 16.8 83 12.6 36 17.9 10 27.8
Central region 1,591 18.3 298 16.9 145 22.1 46 22.9 1 2.8
Eastern region 444 5.1 46 2.6 17 2.6 9 4.5 3 8.3
Amazon region-orinoquía 15 0.2 4 0.2 3 0.5 1 0.5 0 0.0
With chronic comorbidities 6,748 77.5 1,349 76.3 559 85.1 170 84.6 27 75.0
1 pathology 2,914 33.5 595 33.7 232 35.3 52 24.9 12 33.3
2 pathologies 2,132 24.5 426 24.1 175 23.1 70 34.8 9 25.0
≥3 pathologies 1702 19.5 328 18.6 152 23.1 48 23.9 6 16.7
Cardiovascular pathologies 3,998 45.9 776 43.9 314 47.8 71 35.3 10 27.8
Psychiatric pathologies 2013 23.1 407 23.0 155 23.6 56 27.9 13 36.1
Endocrine pathologies 1924 22.1 365 20.7 147 22.4 30 14.9 4 11.1
Urological pathologies 1,533 17.6 285 16.1 159 24.2 47 23.4 5 13.9
Neurological pathologies 696 8.0 170 9.6 95 14.5 91 45.3 7 19.4
Use of antidementiants 6,571 75.4 897 50.8 314 47.8 50 24.9 9 25.0
Rivastigmine 3,917 45.0 686 38.8 192 29.2 42 20.9 6 16.7
Memantine 3,372 38.7 238 13.5 134 20.4 8 4.0 4 11.1
Donepezil 146 1.7 13 0.7 5 0.8 0 0.0 0 0.0
Galantamine 134 1.5 21 1.2 8 1.2 1 0.5 0 0.0
Use of antipsychotics 3,139 36.0 712 40.3 279 42.5 70 34.8 22 61.1
Atypical 2,680 30.8 537 30.4 226 34.4 66 32.8 17 47.2
Quetiapine 2031 23.3 416 23.5 178 27.1 49 24.4 12 33.3
Risperidone 447 5.1 52 2.9 18.0 2.7 6 3.0 2 5.6
Clozapine 217 2.5 61 3.5 21 3.2 10 5.0 3 8.3
Typical 705 8.1 232 13.1 74 11.3 5 2.5 7 19.4
Levomepromazine 427 4.9 127 7.2 37 5.6 5 2.5 4 11.1
Haloperidol 314 3.6 129 7.3 42 6.4 1 0.5 3 8.3
Pipothiazine 4 0.0 2 0.1 0 0.0 0 0.0 0 0.0
Comedications
Antihypertensives and diuretics 5,267 60.5 1,078 61.0 439 66.8 103 51.2 15 41.7
Antidepressants 3,922 45.0 851 48.2 321 48.9 88 43.8 16 44.4
Non-opioid pain relievers 2,786 32.0 593 33.6 228 34.7 77 38.3 12 33.3
Antiulcer 2,517 28.9 572 32.4 214 32.6 67 33.3 14 38.9
Platelet antiaggregants 2,353 27.0 472 26.7 250 38.1 44 21.9 6 16.7

*Other dementias: Includes dementia in Huntington’s disease, frontotemporal dementia, and dementia in human immunodeficiency virus infection.