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. 2021 May 31;12:697437. doi: 10.3389/fendo.2021.697437

Table 2.

Multivariate Cox regression analysis of Waist-BMI Ratio with cause-specific mortality.

Overall mortality Cardiovascular mortality
Event rate/1000 person-years Model I Model II Model III Event rate/1000 person-years Model I Model II Model III
Waist-BMI Ratio
As continuous variables 13.65 3.55 (3.08, 4.09) <0.001 1.60 (1.34, 1.90) <0.001 1.78 (1.48, 2.13) <0.001 2.84 4.11 (3.07, 5.51) <0.001 1.30 (0.91, 1.85) 0.153 1.77 (1.25, 2.52) 0.001
As categorical variables (quintiles)
Q1 7.47 Reference Reference Reference 1.37 Reference Reference Reference
Q2 8.30 0.97 (0.82, 1.15) 0.760 0.89 (0.77, 1.03) 0.105 0.95 (0.81, 1.11) 0.525 1.76 1.09 (0.76, 1.57) 0.631 0.91 (0.65, 1.28) 0.587 1.05 (0.73, 1.51) 0.796
Q3 11.12 1.23 (1.06, 1.43) 0.006 0.92 (0.80, 1.06) 0.262 0.96 (0.82, 1.12) 0.579 1.97 1.19 (0.93, 1.54) 0.171 0.74 (0.56, 0.99) 0.042 0.87 (0.66, 1.15) 0.326
Q4 14.80 1.57 (1.36, 1.83) <0.001 1.03 (0.89, 1.18) 0.710 1.10 (0.95, 1.28) 0.198 3.30 1.77 (1.29, 2.43) <0.001 0.90 (0.64, 1.26) 0.539 1.19 (0.85, 1.68) 0.312
Q5 27.84 2.64 (2.28, 3.06) <0.001 1.27 (1.08, 1.51) 0.005 1.40 (1.17, 1.67) <0.001 6.11 3.02 (2.30, 3.96) <0.001 1.02 (0.73, 1.42) 0.913 1.34 (0.95, 1.88) 0.094
P for trend <0.001 <0.001 <0.001 <0.001 0.490 0.026

Data are hazard ratios (HRs), 95% confidence intervals (95% CIs), and P-value.

Model I adjust for none.

Model II adjust for age, gender, and race.

Model III adjust for age, gender, race, smoking, SBP, HDL-cholesterol, total cholesterol, eGFR, comorbidities (hypertension, diabetes, and cardiovascular disease), and medicine use (antihypertensive drugs, hypoglycemic agents, lipid-lowering drugs, and antiplatelet drugs).