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. 2021 May 17;11:643416. doi: 10.3389/fonc.2021.643416

Table 2.

Clinicopathological characteristics of 42 surgically confirmed PTC patients.

Clinicopathological characteristics Value PC expression P
High Low
Gender
male 14 5 9 0.491
female 28 7 21
Age (Y), Mean ± SD 42.3 ± 1.9
≥55, n (%) 8 (19.0%) 3 5 0.668
<55, n (%) 34 (81.0%) 9 25
Tumor size (mm) ≥5, n (%) 33 (78.6%) 11 27 1
<5, n (%) 9 (21.4%) 1 3
CLNM Positive 15 (35.7%) 11 16 0.031*
Negative 27 (64.3%) 1 14
Extrathyroidal extension Positive 27 (64.3%) 6 9 0.292
Negative 15 (35.7%) 6 21
Multifocal tumor Positive 14 (33.3%) 6 8 0.169
Negative 28 (66.7%) 6 22
Bilateral distribution Positive 21 (50%) 7 14 0.734
Negative 21 (50%) 5 16
TNM stage I + II 29 (69%) 8 21 1
III + IV 13 (31%) 4 9

PTC, papillary thyroid carcinoma; CLNM, central lymph nodal metastasis; PC, pyruvate carboxylase, TNM, tumor-node-metastasis. *P <0.05.