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. 2021 May 17;11:643416. doi: 10.3389/fonc.2021.643416

Table 3.

Clinicopathological characteristics of 71 thyroid nodule patients.

Clinicopathological characteristics Value PC expression P
High Low
Gender
male 27 11 16 0.807
female 44 20 24
Age (Y), Mean ± SD 44.5 ± 1.5
≥55, n (%) 20 (28.3%) 11 15 1
<55, n (%) 51 (71.8%) 20 25
Cytology diagnosis (71)
PTC 52 (73.2%) 28 24 0.006*
Benign nodule 19 (26.3%) 3 16
Surgically diagnosed PTC (34)
CLNM Positive 17 (50.0%) 11 6 0.037*
Negative 17 (50.0%) 4 12
Tumor size (mm) ≥5, n (%) 25 (73.5%) 11 14 1
<5, n (%) 9 (26.5%) 4 4
Extrathyroidal extension Positive 16 (47.1%) 7 9
Negative 18 (52.9%) 8 9 1
Multifocal tumor Positive 27 (79.4%) 12 15 1
Negative 7 (20.6) 3 3
Bilateral distribution Positive 13 (38.2%) 7 9 1
Negative 21 (61.8%) 8 9
TNM stage I + II 28 (82.4%) 14 13 0.186
III + IV 6 (17.6%) 1 5

PTC, papillary thyroid carcinoma; CLNM, central lymph nodal metastasis; PC, pyruvate carboxylase; TNM, tumor-node-metastasis. *P <0.05.