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. 2021 May 17;11:643416. doi: 10.3389/fonc.2021.643416

Table 4.

Univariable and multivariate analyses of predictive factors for CLNM in patients with PTC after FNA.

Variable		Univariate analysis			Multivariate analysis
		P	OR	95% CI	P	OR	95% CI
Gender	male	0.493	1.607	0.414–6.240
Gender	female	0.493	1
Ages (years)	<55	0.034*	6.667	1.151–38.598	0.045*	37.665	1.088–1304.1
Ages (years)	≥55	0.034*	1			1
Tumor size (cm³)	<5	0.698	1.354	0.293–6.261
Tumor size (cm³)	≥5	0.698
PC		0.029*	1.472	1.04–2.085	0.039*	1.728	1.028 – 2.906
Extrathyroidal extension	Positive	0.174	2.619	0.655–10.478
Extrathyroidal extension	Negative	0.174	1
Multifocal tumor	Positive	0.216	0.320	0.053–1.949
Multifocal tumor	Negative	0.216	1
Bilateral distribution	Positive	0.724	1.283	0.321–5.134
Bilateral distribution	Negative	0.724
TNM stage	I + II	0.102	6.667	0.684–64.772
TNM stage	III + IV	0.102	0.2

CLNM, central lymph nodal metastasis; PC, pyruvate carboxylase; CI, confidence interval; OR, odds ratio; TNM, tumor-node-metastasis. *P <0.05.