Table 2.

Hydrodynamic diameter of NCs produced with different oils after freezing/thawing. For p-values the initial size and the size of the thawed particles were compared.

	n-Dodecane		Rapeseed oil		Olive oil		Linseed oil		Cotton seed oil		Almond oil
	Size average [nm]	PDI	Size average [nm]	PDI	Size average [nm]	PDI	Size average [nm]	PDI	Size average [nm]	PDI	Size average [nm]	PDI
Initial size	655.0 ± 27.4	0.11 ± 0.02	862.2 ± 59.5	0.24 ± 0.08	835.8 ± 70.4	0.17 ± 0.05	760.4 ± 79.3	0.30 ± 0.06	709.4 ± 80.4	0.21 ± 0.06	816.4 ± 95.6	0.18 ± 0.06
Liquid nitrogen	673.7 ± 22.3n.s.	0,1 ± 0.02	903.3 ± 139.7n.s.	0.22 ± 0.08	856.4 ± 69.9n.s.	0.12 ± 0.05	1098.3 ± 178.1 *	0.32 ± 0.04	998.5 ± 59.6 *	0.24 ± 0.02	814.6 ± 121.4n.s.	0.21 ± 0.12
−80 °C	722.1 ± 16.3 *	0.21 ± 0.03	1005.9 ± 182.4 *	0.29 ± 0.05	891.3 ± 8.4n.s.	0.22 ± 0.09	1984.3 ± 414.0 *	0.14 ± 0.06	972.5 ± 69.6 **	0.26 ± 0.04	896.9 ± 155.1n.s.	0.34 ± 0.09
−20 °C	852.2 ± 9.2 *	0.18 ± 0.04	2374.0 ± 592.9 *	0.45 ± 0.31	2500.0 ± 1336.1 *	0.52 ± 0.07	2032.0 ± 1320.3 *	0.94 ± 0.10	1782.9 ± 1019.4 *	0.81 ± 0.04	3119.0 ± 3005.2 *	0.51 ± 0.06