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CNV-based genetic mutation prediction. (A) AUC distributions of CNV-based predictions for top 20 genes with the highest mutation frequencies selected from TCGA lung adenocarcinoma mutation data. (B) ROC curves and corresponding AUC values of TP53 mutation status in the TCGA training and test sets. (C) Elastic Net-selected CNV segments and whole chromosomal arms and their coefficients selected for prediction models for TP53 mutation.
