TABLE 2.
Epidemiologic Features, Therapy Pattern, and Outcomes of the Acute Respiratory Distress Syndrome Cohorts
| Epidemiologic Features, Therapy Pattern, and Outcomes | Computer Phenotyped (N = 3,169) | Clinician Documented (N = 1,257) | p |
|---|---|---|---|
| Age, mean ± sd | 63.1 ± 15.9 | 59.2 ± 16.9 | < 0.0001a |
| Male sex, n (%) | 1,782 (56.2) | 717 (57.0) | 0.73b |
| Sequential Organ Failure Assessment score, median (interquartile range) | 9 (6–12) | 7 (4–10) | < 0.0001a |
| Acute Physiology and Chronic Health Evaluation IV score, median (interquartile range) | 76 (58–98) | 63 (45–87) | < 0.0001a |
| Invasive MV use, n (%) | 3,139 (99.1) | 901 (71.8) | < 0.0001b |
| Duration of invasive MV (d), median (interquartile range) | 2.5 (1.1–5.6) | 1.4 (0–5.5) | < 0.0001a |
| ICU mortality, n (%) | 653 (20.6) | 206 (16.8) | < 0.0001b |
| ICU LOS (d), median (interquartile range) | 5.1 (2.7–8.9) | 4.2 (1.5–10.2) | < 0.0001a |
| Hospital mortality, n (%) | 860 (27.1) | 323 (25.7) | 0.34b |
| Hospital LOS (d), median (interquartile range) | 11.2 (6.2–20.0) | 13.2 (6.4–24.6) | < 0.0001a |
LOS = length of stay, MV = mechanical ventilation.
ap comes from Wilcoxon rank-sum test.
bp comes from χ2.