Figure 7.

ACs expressing KRAS^G12D were more effective than DUs in inducing formation of early pancreatic-cancer-like lesions in vivo

(A and B) Histology of lesions grown from KRAS^G12D-expressing DUs (A, N = 9) or ACs (B, N = 10) transplanted into the mouse pancreas. Tissues were stained with nuclear red. Scale bars, 100 μm.

(C and D) Expression of human KRT19 (red), Ki67 (green), KRT7 (teal), MUC5AC (yellow), and SOX9 (purple) in lesions grown from KRAS^G12D-expressing DUs (C) or ACs (D). Scale bars, 100 μm.