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. 2021 Apr 26;13(10):13663–13679. doi: 10.18632/aging.202909

Table 1. Genetic alterations affecting CENPU in 37419 unique samples from the COSMIC database (297 unique samples with mutations in the COSMIC database).

Genetic alteration Number Percentage (%)
total number 297
Percentage (%)
total number 37419
Nonsense substitution 6 2.02 0.0002
Missense substitution 94 31.65 0.0025
Synonymous substitution 22 7.41 0.0006
Inframe insertion 0 0 0
Frameshift insertion 3 1.01 8.02E-05
Inframe deletion 0 0 0
Frameshift deletion 1 0.34 2.67E-05
Complex mutation 0 0 0
Other 30 10.10 0.0008