Table 1. Characterization of the study subjects.
| Variable |
CD4/CD8<1.4 N = 22 (Group A) |
1.4<CD4/CD8<2 N = 19 (Group B) |
CD4/CD8>2 N = 24 (Group C) |
P (K-W) |
p (M-W) (A vs. B) |
p (M-W) (A vs. C) |
p (M-W) (B vs. C) |
| CD4/CD8 ratio | 1.05 [0.90 – 1.23] | 1.75 [1.56 – 1.90] | 3.03 [2.18 – 4.06] | < 0.001 | 0.002 | < 0.001 | 0.001 |
| Age (years) | 80 [72 - 89] | 76 [71 - 84] | 77 [65 - 87] | 0.561 | 0.289 | 0.415 | 0.903 |
| Male sex, n (%) | 10 (35.7) | 11 (39.3) | 7 (25) | 0.071 | 0.536 | 0.361 | 0.058 |
| CD4 T-cells (cell/mm3) | 765 [610 - 985] | 844 [730 - 1059] | 898 [584 - 1285] | 0.545 | 0.284 | 0.429 | 0.807 |
| CD8 T-cells (cell/mm3) | 689 [470 - 988] | 486 [384 - 630] | 270 [151 - 419] | < 0.001 | 0.033 | < 0.001 | 0.002 |
| B lymphocytes (cell/mm3) | 152 [86 - 231] | 104 [63 - 127] | 127 [68 - 306] | 0.583 | 0.374 | 1 | 0.412 |
| NK lymphocytes (cell/mm3) | 221 [123 - 607] | 161 [66 - 230] | 194 [107 - 266] | 0.458 | 0.304 | 0.387 | 0.661 |
| Monocytes (%) | 6.7 [5.6 – 7.6] | 6.9 [5.1 – 7.6] | 6 [5.3 – 7.4] | 0.606 | 0.948 | 0.391 | 0.398 |
| Neutrophils (%) | 58.4 [53.6 – 65.5] | 58 [53.1 – 63.2] | 62.7 [55.6 - 66] | 0.398 | 0.565 | 0.416 | 0.187 |
| Eosinophils (%) | 3.6 [1.7 – 4.2] | 3.4 [1.8 – 4.3] | 3.2 [2.2 – 4.7] | 0.983 | 0.824 | 0.955 | 0.919 |
| Basophils (%) | 0.2 [0.1 – 0.3] | 0.2 [0.1 – 0.4] | 0.3 [0.2 – 0.4] | 0.682 | 0.810 | 0.381 | 0.601 |
| Platelets (x109/L) | 244 [184 - 321] | 197 [165 - 253] | 212 [168 - 287] | 0.214 | 0.089 | 0.239 | 0.533 |
| Anti-CMV IgG (AU/mL) | 34.4 [10.5 – 41.5] | 21.8 [12.2 – 25.8] | 24.3 [6.8 – 43.5] | 0.038 | 0.013 | 0.065 | 0.549 |
Notes: Quantitative variables are expressed as median [IQR], and categorical variables are expressed as the number of cases (%). Variables with a p-value <0.05 were considered statistically significant, as shown in bold. Abbreviations: K-W, nonparametric Kruskal-Wallis test; M-W, nonparametric Mann-Whitney U test.