Table 3. Descriptive statistics of epigenetic aging indicators according to the combined healthy lifestyle score.

Characteristics	All	0-1	2	3	4	P
Number of participants	286	50	94	97	45
Chronological age (mean (SD))	48.9(10.6)	49.9(11.2)	49.4 (10.3)	48.6 (10.6)	47.4(10.6)	0.646
Horvath_mage (mean (SD))	53.6 (8.9)	54.1 (9.3)	54.0 (8.3)	53.6 (9.2)	52.3 (8.9)	0.720
Li_mage (mean (SD))	48.4 (10.6)	49.0 (10.7)	49.2 (10.4)	48.4(10.9)	46.2 (9.9)	0.446
Horvath_AA (mean (SD))	0.0 (3.7)	-0.3(3.9)	0.1 (3.0)	0.2 (4.3)	-0.2 (3.7)	0.860
Li_AA(mean (SD))	0.0 (4.3)	-0.3 (3.1)	0.4 (4.3)	0.2 (5.2)	-0.9 (3.0)	0.401
Horvath_IEAA (mean (SD))	0.0 (3.5)	0.2 (3.8)	0.1 (2.9)	0.1 (4.0)	-0.6 (3.5)	0.716
Li_IEAA (mean (SD))	0.0 (4.1)	-0.2 (3.1)	0.3 (4.1)	0.3 (4.8)	-1.0 (3.2)	0.268

Note: mage: DNA methylation age; AA:age acceleration; IEAA: intrinsic epigenetic age acceleration, Li and Horvath present two algorithms for calculating mage respectively.