Table 3. Effects of NF-κB p65 silencing on heart functions.
Group | LVPWD (mm) | IVSD (mm) | LVEDD (mm) | LVESD (mm) | LVEF (%) | FS (%) |
Model + sh-NC | 1.07±0.12 | 2.64±0.31 | 6.17±0.72 | 4.12±0.43 | 32.76±4.54 | 15.23±1.74 |
Model + sh-NF-κB p65 | 1.36±0.19* | 1.24±0.16* | 2.91±0.39* | 1.54±0.21* | 67.34±7.84* | 23.16±2.69* |
Note: *p < 0.05 vs. model + sh-NC group. NC, negative control; miR-155, microRNA-155; BNDF, brain-derived neurotrophic factor; LVPWD, left ventricular posterior wall thickness; IVSD, interventricular septal dimension; LVEDD, left ventricular end diastolic diameter; LVEF, left ventricular ejection fraction; FS, fractional shortening.