Skip to main content
. 2020 Nov 18;13(10):14482–14498. doi: 10.18632/aging.103640

Table 3. Effects of NF-κB p65 silencing on heart functions.

Group LVPWD (mm) IVSD (mm) LVEDD (mm) LVESD (mm) LVEF (%) FS (%)
Model + sh-NC 1.07±0.12 2.64±0.31 6.17±0.72 4.12±0.43 32.76±4.54 15.23±1.74
Model + sh-NF-κB p65 1.36±0.19* 1.24±0.16* 2.91±0.39* 1.54±0.21* 67.34±7.84* 23.16±2.69*

Note: *p < 0.05 vs. model + sh-NC group. NC, negative control; miR-155, microRNA-155; BNDF, brain-derived neurotrophic factor; LVPWD, left ventricular posterior wall thickness; IVSD, interventricular septal dimension; LVEDD, left ventricular end diastolic diameter; LVEF, left ventricular ejection fraction; FS, fractional shortening.