Table 5. Effects of miR-155 and BDNF inhibition on heart functions in HF rats.

Group	LVPWD (mm)	IVSD (mm)	LVEDD (mm)	LVESD (mm)	LVEF (%)	FS (%)
Model + NC antagomir	0.84±0.09	1.37±0.34	3.96±0.54	1.92±0.39	33.17±1.37	11.64±1.27
Model + miR-155 antagomir	1.23±0.16*	0.78±0.17*	1.25±0.34*	1.01±0.21*	68.16±2.76*	23.38±2.14*
Model + miR-155 antagomir + sh-NC	1.34±0.15	0.62±0.14	1.42±0.28	1.16±0.23	69.14±2.72	23.08±2.31
Model + miR-155 antagomir + sh-BDNF	0.76±0.08*	1.41±0.29*	3.73±0.79*	2.07±0.32*	31.05±1.34*	11.25±0.96*

Note: *p < 0.05 vs. model + NC antagomir or model + miR-155 antagomir + sh-NC group. HF, heart failure; NC, negative control; miR-155, microRNA-155; BNDF, brain-derived neurotrophic factor; LVPWD, left ventricular posterior wall thickness; IVSD, interventricular septal dimension; LVEDD, left ventricular end diastolic diameter; LVEF, left ventricular ejection fraction; FS, fractional shortening.