Table 6. Effects of miR-155 and BDNF inhibition on heart hemodynamics in HF rats.

Group	LVSP (mm Hg)	LVEDP (mm Hg)	HR (bpm)	+dp/dt (mm Hg/s)	-dp/dt (mm Hg/s)
Model + NC antagomir	53.64±5.86	22.46±2.47	249.21±26.85	1921.26±203.16	1017.24±129.24
Model + miR-155 antagomir	93.34±9.46*	5.34±0.71*	261.37±25.89	4054.23±463.79*	2364.69±217.45*
Model + miR-155 antagomir + sh-NC	109.56±15.24	4.21±0.63	279.34±31.26	4212.34±465.79	2169.37±301.75
Model + miR-155 antagomir + sh-BDNFl	49.67±5.79*	21.04±2.76*	278.76±34.19	1863.27±197.64*	996.17±107.65*

Note: *p < 0.05 vs. model + NC antagomir or model + miR-155 antagomir + sh-NC group. HF, heart failure; NC, negative control; miR-155, microRNA-155; BNDF, brain-derived neurotrophic factor; LVSP, left ventricular systolic pressure; LVEDP, left ventricular end diastolic pressure; HR, heart rate; +dp/dt, rate of increase in left ventricular pressure; -dp/dt, rate of decrease in left ventricular pressure.