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. 2020 Nov 18;13(10):14482–14498. doi: 10.18632/aging.103640

Table 7. Effects of Sirt1 overexpression on heart functions in HF rats.

Group LVPWD (mm) IVSD (mm) LVEDD (mm) LVESD (mm) LVEF (%) FS (%)
Model + oe-NC 0.97±0.12 1.36±0.14 3.65±0.84 1.87±0.24 34.18±3.76 17.08±1.19
Model + oe-Sirt1 1.42±0.16* 0.68±0.12* 1.62±0.23* 0.97±0.15* 70.31±7.79* 24.07±3.06*

Note: *p < 0.05 vs. model + oe-NC group. HF, heart failure; NC, negative control; LVPWD, left ventricular posterior wall thickness; IVSD, interventricular septal dimension; LVEDD, left ventricular end diastolic diameter; LVEF, left ventricular ejection fraction; FS, fractional shortening.