Table 8. Effects of Sirt1 overexpression on heart hemodynamics in HF rats.

Group	LVSP (mm Hg)	LVEDP (mm Hg)	HR (bpm)	+dp/dt (mm Hg/s)	-dp/dt (mm Hg/s)
Model + oe-NC	58.49±6.94	25.46±2.75	272.45±32.16	2106.28±234.67	1123.71±167.49-
Model + oe-Sirt1	105.34±12.46*	5.24±0.61*	251.64±34.16	4316.94±310.37*	2696.49±302.57*

Note: *p < 0.05 vs. model + oe-NC group. HF, heart failure; NC, negative control; LVSP, left ventricular systolic pressure; LVEDP, left ventricular end diastolic pressure; HR, heart rate; +dp/dt, rate of increase in left ventricular pressure; -dp/dt, rate of decrease in left ventricular pressure.