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. 2021 May 19;13(10):13560–13570. doi: 10.18632/aging.202862

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Copyright: © 2021 Gao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Molecular changes in the progression of Alzheimer’s disease. (A) The differentially expressed genes between moderate and mild AD patients. (B) Differentially expressed genes between severe and moderate AD patients. (C) Modules significantly up or down in the STEM results. (D) The trend in gene expression in significantly up-regulated or down-regulated modules. (E) The expression trend of potential risk genes in different stages of AD in patients. The enrichment results of persistent disorder genes include biological function (F) and the KEGG pathway (G).