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. 2021 Jun 2;17(6):e1009035. doi: 10.1371/journal.pcbi.1009035

Table 4. Summary of the asynchronous updating results for the EMT model from [55] after 100 asynchronous updating simulations for each of the 256 possible initial states.

The order of species is (NICD, Notch, TP53, TP63_TP73, miRNA, EMTreg, ECM, DNAdam). The network splits into four mutually exclusive sub-networks depending on the two parameters ECM and DNAdam. Initial states for three of those sub-networks can run into two different attractors with varying frequency.

(ECM, DNAdam) SS frequency
(0, 0) (0, 0, 0, 0, 0, 0, 0, 0) 0.61
(0, 0, 1, 0, 1, 0, 0, 0) 0.39
(0, 1) (0, 0, 1, 0, 1, 0, 0, 1) 1.0
(1, 0) (0, 0, 1, 0, 1, 0, 1, 0) 0.52
(1, 1, 0, 0, 0, 1, 1, 0) 0.48
(1, 1) (0, 0, 1, 0, 1, 0, 1, 1) 0.79
(1, 1, 0, 0, 0, 1, 1, 1) 0.21