Table 4. Summary of the asynchronous updating results for the EMT model from [55] after 100 asynchronous updating simulations for each of the 256 possible initial states.
The order of species is (NICD, Notch, TP53, TP63_TP73, miRNA, EMTreg, ECM, DNAdam). The network splits into four mutually exclusive sub-networks depending on the two parameters ECM and DNAdam. Initial states for three of those sub-networks can run into two different attractors with varying frequency.
(ECM, DNAdam) | SS | frequency |
---|---|---|
(0, 0) | (0, 0, 0, 0, 0, 0, 0, 0) | 0.61 |
(0, 0, 1, 0, 1, 0, 0, 0) | 0.39 | |
(0, 1) | (0, 0, 1, 0, 1, 0, 0, 1) | 1.0 |
(1, 0) | (0, 0, 1, 0, 1, 0, 1, 0) | 0.52 |
(1, 1, 0, 0, 0, 1, 1, 0) | 0.48 | |
(1, 1) | (0, 0, 1, 0, 1, 0, 1, 1) | 0.79 |
(1, 1, 0, 0, 0, 1, 1, 1) | 0.21 |