Table 5.
Inhibitory effects of nitroxide-NSAID conjugates on NCI-H1299 cell growth.
| Compound | Concentration (μM) | % Growth |
|---|---|---|
| Aspirin | 90 | 103 ± 4 |
| Aspirin | 900 | 49 ± 2* |
| Tempol | 90 | 100 ± 4 |
| Tempol | 900 | 98 ± 5 |
| Aspirin + Tempol | 90 | 102 ± 6 |
| Aspirin + Tempol | 900 | 53 ± 4* |
| 27 | 18 | 97 ± 3 |
| 27 | 180 | 13 ± 1* |
The mean value ± S.D. of 3 experiments each repeated in duplicate is shown using NCI-H1299 cells
p < 0.05, using the Student’s t-test.