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. Author manuscript; available in PMC: 2021 Jun 14.
Published in final edited form as: Eur J Med Chem. 2018 Jan 31;147:34–47. doi: 10.1016/j.ejmech.2018.01.077

Table 5.

Inhibitory effects of nitroxide-NSAID conjugates on NCI-H1299 cell growth.

Compound Concentration (μM) % Growth

Aspirin 90 103 ± 4
Aspirin 900 49 ± 2*
Tempol 90 100 ± 4
Tempol 900 98 ± 5
Aspirin + Tempol 90 102 ± 6
Aspirin + Tempol 900 53 ± 4*
27 18 97 ± 3
27 180 13 ± 1*

The mean value ± S.D. of 3 experiments each repeated in duplicate is shown using NCI-H1299 cells

*

p < 0.05, using the Student’s t-test.