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. 2021 May 25;8:655285. doi: 10.3389/fmolb.2021.655285

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Copyright © 2021 Yang, Yuan, Yang, Du, Qin, Wang, Zhou, Wu, He, Feng, Xiang, Qu, Liu, Qin and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Accuracy of the methylation level of the 8 DMSs in distinguishing asthma patients from HCs. (A) ROC curve analysis of differential CpG sites Chr4:75310649-1, Chr20:32274088, Chr20:32274358, Chr6:108882977, Chr16:55514392, Chr16:55514437, Chr1:163291825, and Chr17:7591672, respectively. (B) The ROC curve of the predicted probability of the 8 DMSs. (C) A PCA plot consisting of the methylation levels of the 8 DMSs in HCs and asthma patients.