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PTEN acted as the target of miR-18a. (a) The prediction binding sites of miR-18a and PTEN. (b) Detection of the expression of PTEN in EC tissues. (c) Pearson's analysis of the relationship between PTEN and miR-18a. (d) The relative mRNA and (e) protein expression affected by miR-18a mimic or inhibitor. (f) The luciferase activity detected in ECA109 cells after treated with miR-18a mimic or inhibitor and PTEN-WT or PTEN-MuT.
