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Costaining of G3BP1 (green) and the pyramidal neuron marker CaMK2 (red), as well as cell morphology, suggest that cells with high-density G3BP1-positive granules are likely to be pyramidal neurons. This pattern of reactivity was observed for HD and control cases. Nuclei were stained with DAPI (blue). Data are representative of 2 HD and 2 control samples. Scale bar: 20 μm.
