Table 3.

Univariate and multivariate analyses factors related to recurrences in this study cohort

	Univariate analysis		Multivariate analysis
	OR (95% CI)	p value	OR (95% CI)	p value
Brinkman Index (> 1000 vs ≤ 1000)	3.000 (0.859–10.476)	0.167
Tumor size on CT (> 30 mm vs ≤ 30 mm)	1.125 (0.373–3.386)	0.834
Consolidation/tumor ratio (> 0.75 vs ≤ 0.75)	0.750 (0.248–2.271)	0.259
SUV of PET-CT (> 5 vs ≤ 5)	0.903 (0.260–3.138)	0.873
Surgical procedure (complex vs simple segmentectomy)	2.217 (0.692–7.097)	0.180
Lymph-node dissection (ND0 or ND1 vs ND2)	0.750 (0.248–2.271)	0.611
Pathologic tumor size (> 30 mm vs ≤ 30 mm)	2.331 (0.759–7.159)	0.139
Histology (adenocarcinoma vs others)	0.889 (0.295–2.676)	0.834
Visceral pleural invasion (positive vs negative)	2.184 (0.714–6.678)	0.171
Lymphatic vessel invasion (positive vs negative)	6.000 (1.425–25.267)	0.0146	1.763 (0.425–7.321)	0.435
Blood vessel invasion (positive vs negative)	14.375 (1.670–123.706)	0.0152	2.146 (0.634–7.269)	0.220
Pathologic lymph-node involvement (N1 or N2 vs N0)	2.464 (0.492–12.354)	0.273
Pathologic stage (IB-IIIA vs IA)	2.044 (0.627–6.669)	0.217
PPMM with NCD RC (≥ 5.2% vs < 5.2%)	3.975 (1.015–15.572)	0.0476	3.149 (0.777–12.877)	0.110

CI confidence interval, CT computed tomography, NCD National Clinical Database, ND nodal dissection, OR odds ratio, PET positron emission tomography, PPMM predictive probability of perioperative mortality or major morbidity, RC Risk Calculator, SUV standardized uptake value