Table 2.

Histological evaluation of hearts and pancreata in saline, wt CVB3, Mt 10-infected, and Mt 10-infected and challenged mice.

Parameters	Saline	wt CVB3	Mt 10	Mt 10 + wt CVB3
Heart
Incidence	0/9 (0.0)	12/18 (66.7)	0/16 (0.0)	0/17 (0.0)
Mortality	0/9 (0.0)	9/18 (50)	0/16 (0.0)	0/17 (0.0)
Myocardial lesions	0.0 (0.0)a	34.5 ± 13.3	0.0 (0.0)a	0.0 (0.0)a
Pancreas
Incidence	0 (0.0)	16/18 (88.9)	1/16 (6.2)	0 (0.0)
Atrophy	0 (0.0)a	16/18 (88.9)	1/16 (6.2)a	0 (0.0)a
Inflammation	0 (0.0)a	16/18 (88.9)	0/16 (0.0)a	0 (0.0)a
Necrosis	0 (0.0)	0/18 (0.0)	0/16 (0.0)	0 (0.0)
Mineralization	0 (0.0)	0/18 (0.0)	0/16 (0.0)	0 (0.0)

() Indicates percentages.

^aDenotes significant differences in comparison with wt CVB3 group (p < 0.0001).