Fig. 1. Deer mouse range and predicted susceptibility to SARS-CoV-2.

a Phylogeny showing the relationships among selected members of the Cricetidae family with mice and humans. b Geographical distribution of deer mice (based on data from Hall, 1981)⁴³. c Alignment of human ACE2 (hACE2) amino acid residues known to confer efficient binding of the RBD of SARS-CoV-2 spike with the corresponding ACE2 amino acid residues from selected members of the Cricetidae family and other naturally or experimentally susceptible host species. The physiochemical properties of the amino acids residues are indicated: nonpolar (yellow), polar (green), acidic (red), and basic residues (blue).