Figure 5.

Relationship between nitrosamine/DMF degradation and arginine metabolism as observed in our experiments. Genes labelled in black correspond to deletion strains that displayed growth defects in our experiments, while those in blue did not show fitness defects. The dashed arrow with question marks (in yellow) means the reaction is hypothetical, i.e. depicting NH₄ from nitrosamine degradation entering the arginine biosynthetic pathway. In the diagram, only metabolic intermediates of nitrosamine/DMF that we screened are shown.