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. 2021 Jun 14;11:12503. doi: 10.1038/s41598-021-91913-w

Table 1.

Control variables, their coded values and actual values included in optimisation.

Control variables Units Symbol Coded levels
− 1.68 − 1 0  + 1  + 1.68
Ethanol concentration %, v/v X1 7.95 25 50 75 92.05
Temperature °C X2 14.77 25 40 55 65.23
Sonication time min X3 3.18 10 20 30 36.82