Figure 2. Protein network showing genes differentially expressed at the pre-pregnancy baseline within the same functional network.

A large proportion of the 89 genes differentially expressed between RA_improved women and healthy women at the pre-pregnancy baseline encode proteins that belong to a common functional network, based on protein interactions data from the STRING database. Most of the under-expressed genes (blue circles) formed a tight cluster, distinct from the over-expressed genes (orange circles).