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. 2021 Jun 1;12:682232. doi: 10.3389/fphar.2021.682232

TABLE 2.

Summary of meta-analysis.

Outcomes No. of studies No. of participants Effect size (95% CI) I2
28-day mortality 9 708 RR, 0.66 (0.56, 0.77) 0
HR 11 749 SMD, −1.70 (−2.24, −1.17) 89.6%
MAP 9 611 SMD, 0.13 (−0.03, 0.29) 0
cTnI 6 329 SMD, −1.61 (−2.06, −1.16) 68.6%
Lac 9 507 SMD, −0.16 (−0.80, 0.49) 91.7%
CI 7 399 SMD, 0.13 (−0.82, 1.08) 94.9%
SVI 6 339 SMD, 0.67 (−0.04, 1.39) 89.8%

HR, heart rate; MAP, mean arterial pressure; Lac, lactate; CI, cardiac index; SVI, stroke volume index; RR, relative risks; WMD, weighted mean difference.