Table 4.
Pairwise ROC curve comparisons expressed as differences in AUC and P-values for the study.
| d-AUC (P*) | ADNEXN125 | RMI-I | RMI-II | RMI-III |
|---|---|---|---|---|
| ADNEX125 | 0.0002 (-0.012-0.012) P=0.977 |
0.074 (0.039-0.109) P<0.0001 |
0.109 (0.066-0.151) P<0.0001 |
0.118 (0.076-0.160) P<0.0001 |
| ADNEXN125 | / | 0.074 (0.040-0.108) P<0.0001 |
0.108 (0.064-0.153) P<0.0001 |
0.118 (0.073-0.163) P<0.0001 |
| RMI-I | / | / | 0.035 (0.010-0.060) P=0.007 |
0.044 (0.017-0.071) P=0.001 |
| RMI-II | / | / | / | 0.010 (0.003-0.016) P=0.002 |
*Comparisons of area under the curves (AUCs) of prediction models using Delong’s test; methods in left column are used as reference standard for comparisons; d-AUC, differences in area under the curve. Prediction models; ADNEX125, the Assessment of Different NEoplasias in the adneXa model with CA125 level; ADNEXN125, the Assessment of Different NEoplasias in the adneXa model without CA125 level; RMI-I, RMI-II, RMI-III, three variants of the Risk of Malignancy Index. Values in parentheses are 95% CI.