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. 2021 Jun 1;12:685237. doi: 10.3389/fimmu.2021.685237

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Copyright © 2021 Looney, Lorenc, Halushka and Karakousis

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pathway analysis for significantly dysregulated targets of candidate miRNAs. Each shows gprofiler2 (g:OSt) results for a miRNA candidate. g:OSt was used to analyze the association of each miRNAs target genes with Gene Ontology biological processes functional groups (GO : BP). All significant GO : BP associations are reported. miRNAs which do not have GO : BP results listed did not have significant associations with any GO : BP functional group. g:OSt MIRNA was used to determine which miRNA is most significantly associated with each list of dysregulated targets. The top miRNA hit for each is reported.