Table 1.
Characteristics of patients with and without S-gene target failure (SGTF) variants. Values are numbers (percentages)
| Characteristic | Overall (n=839 278) | SGTF (n=592 409) | Non-SGTF (n=246 869) |
|---|---|---|---|
| Age group, years: | |||
| <10 | 44 216 (5.3) | 31 935 (5.4) | 12 281 (5.0) |
| 10-19 | 93 730 (11.2) | 63 084 (10.6) | 30 646 (12.4) |
| 20-29 | 160 857 (19.2) | 115 296 (19.5) | 45 561 (18.5) |
| 30-39 | 165 570 (19.7) | 118 229 (20.0) | 47 341 (19.2) |
| 40-49 | 144 265 (17.2) | 102 684 (17.3) | 41 581 (16.8) |
| 50-59 | 132 211 (15.8) | 93 468 (15.8) | 38 743 (15.7) |
| 60-69 | 63 897 (7.6) | 44 709 (7.5) | 19 188 (7.8) |
| 70-79 | 23 203 (2.8) | 15 726 (2.7) | 7477 (3.0) |
| ≥80 | 11 329 (1.3) | 7278 (1.2) | 4051 (1.6) |
| Female sex | 436 049 (52.0) | 305 230 (51.5) | 130 819 (53.0) |
| Region of residence (PHEC): | |||
| East Midlands | 44 407 (5.3) | 22 913 (3.9) | 21 494 (8.7) |
| East of England | 84 454 (10.1) | 71 250 (12.0) | 13 204 (5.3) |
| London | 169 606 (20.2) | 141 864 (23.9) | 27 742 (11.2) |
| North East | 48 227 (5.7) | 28 120 (4.7) | 20 107 (8.1) |
| North West | 151 897 (18.1) | 94 050 (15.9) | 57 847 (23.4) |
| South East | 128 844 (15.4) | 109 794 (18.5) | 19 050 (7.7) |
| South West | 26 382 (3.1) | 17 235 (2.9) | 9147 (3.7) |
| West Midlands | 117 577 (14.0) | 74 730 (12.6) | 42 847 (17.4) |
| Yorkshire and Humber | 67 884 (8.1) | 32 453 (5.5) | 35 431 (14.4) |
| Ethnicity: | |||
| White | 615 523 (73.3) | 430 930 (72.7) | 184 593 (74.8) |
| Asian | 124 156 (14.8) | 85 829 (14.5) | 38 327 (15.5) |
| Black | 36 778 (4.4) | 28 604 (4.8) | 8174 (3.3) |
| Mixed | 17 880 (2.1) | 13 330 (2.3) | 4550 (1.8) |
| Other | 31 491 (3.8) | 23 816 (4.0) | 7675 (3.1) |
| Unknown | 13 450 (1.6) | 9900 (1.7) | 3550 (1.4) |
| Symptoms present | 717 627 (85.5) | 503 826 (85.0) | 213 801 (86.6) |
| Index of multiple deprivation fifth: | |||
| 1 (most deprived) | 202 957 (24.2) | 132 643 (22.4) | 70 314 (28.5) |
| 2 | 190 807 (22.7) | 136 868 (23.1) | 53 939 (21.8) |
| 3 | 162 121 (19.3) | 117 727 (19.9) | 44 394 (18.0) |
| 4 | 148 798 (17.7) | 106 589 (18.0) | 42 209 (17.1) |
| 5 (least deprived) | 134 595 (16.0) | 98 582 (16.6) | 36 013 (14.6) |
| Specimen collection date: | |||
| 23-29 Nov 2020 | 45 122 (5.4) | 7327 (1.2) | 37 795 (15.3) |
| 30 Nov-6 Dec 2020 | 46 205 (5.5) | 13 143 (2.2) | 33 062 (13.4) |
| 7-13 Dec 2020 | 65 523 (7.8) | 30 817 (5.2) | 34 706 (14.1) |
| 14-20 Dec 2020 | 82 854 (9.9) | 52 214 (8.8) | 30 640 (12.4) |
| 21-27 Dec 2020 | 93 442 (11.1) | 66 222 (11.2) | 27 220 (11.0) |
| 28 Dec 2020-3 Jan 2021 | 135 516 (16.1) | 103 311 (17.4) | 32 205 (13.0) |
| 4-10 Jan 2021 | 132 201 (15.8) | 107 269 (18.1) | 24 932 (10.1) |
| 11-17 Jan 2021 | 103 930 (12.4) | 89 329 (15.1) | 14 601 (5.9) |
| 18-24 Jan 2021 | 76 521 (9.1) | 68 854 (11.6) | 7667 (3.1) |
| 25-31 Jan 2021 | 57 964 (6.9) | 53 923 (9.1) | 4041 (1.6) |
PHEC=Public Health England Centres.