Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 1;9:642108. doi: 10.3389/fcell.2021.642108

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Fang, Sun, Liu, Yang, Lin, Feng, Cruz, Dong, Fang and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Regulation of shear stress accumulation on von Willebrand factor (VWF)-induced P-selectin translocation. The platelets firmly adhered to substrates coated with WTA1, R1308L, and G1324S, respectively. (A) The mean P-selectin-positive platelet fraction F_P, (B) the mean of P-selectin coverage area A_P, and (C) the normalized P-selectin-related fluorescence intensity FI_P; all were well correlated with shear stress accumulation, whether VWF-A1 was mutated or not. All data are shown as mean ± SEM from at least three independent experiments and analyzed by two-way ANOVA for multiple comparisons; ***p < 0.001 compared with the WTA1 group.