Table 3.
Performance Characteristics of Thyroid Fine-Needle Aspiration in Patients With Surgical Pathology or Minimum of 10 Years of Clinical Follow-up
| Cytology Category | All Nodules, No. (%) | Follow-up Available | ||
|---|---|---|---|---|
| No. (%) | NPV, % | PPV, % | ||
| ND/UNS | 673 (13.0) | 335 (17.1) | 94.0 | 6.0 |
| Benign | 3,452 (66.7) | 726 (37.0) | 95.6 | 4.4 |
| AUS/FLUS | 39 (0.8) | 22 (1.1) | 86.4 | 13.6 |
| SFN/FN | 414 (8.0) | 343 (17.5) | 90.1 | 9.9 |
| SFM | 164 (3.2) | 147 (7.5) | 20.4 | 79.6 |
| Malignant | 433 (8.4) | 391 (19.9) | 1.5 | 98.5 |
| Total No. of nodules | 5,175 | 1,964 | 1,373 | 591 |
AUS/FLUS, atypia of undetermined significance/follicular lesion of undetermined significance; ND/UNS, nondiagnostic/unsatisfactory; NPV, negative predictive value; PPV, positive predictive value; SFM, suspicious for malignancy; SFN/FN, suspicious for follicular neoplasm/follicular neoplasm.