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. Author manuscript; available in PMC: 2022 Mar 2.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2020 Nov 20;106:110183. doi: 10.1016/j.pnpbp.2020.110183

Table 3:

Three largest clusters associated with latent variable 1 and latent variable 2. (A-F) Largest clusters for LV1 associations, respectively and (G-L) Largest for LV2. BSR = bootstrap ratio. LV = latent variable.

BSR x y z Region Brodmann Area
(A) LV1{MJ, CNR1 CC+CT, increasing scores on the Perceived Stress Scale and Early Trauma Inventory}, Cluster 1 (Voxels = 118)
Max 3.6 0 18 22 Cingulate Gyrus BA24
Min 3.0 −2 18 26 Cingulate Gyrus BA24
Centroid 3.1 2 14 28 Cingulate Gyrus BA24

(B) LV1{MJ, CNR1 CC+CT, increasing scores on the Perceived Stress Scale and Early Trauma Inventory}, Cluster 2 (Voxels = 34)
Max 3.4 0 50 −14 Medial Frontal Gyrus BA10
Min 3.0 −2 52 −14 Medial Frontal Gyrus BA10
Centroid 3.4 0 50 −14 Medial Frontal Gyrus BA10

(C) LV1{MJ, CNR1 CC+CT, increasing scores on the Perceived Stress Scale and Early Trauma Inventory}, Cluster 3 (Voxels = 22)
Max 3.6 34 −8 58 Precentral Gyrus BA6
Min 3.0 34 −6 56 Precentral Gyrus BA6
Centroid 2.9 32 −6 60 Precentral Gyrus BA6

(D) LV1{CON and CNR1 TT}, Cluster 1 (Voxels = 158)
Max −3.0 40 −78 10 Medial Occipital Gyrus BA19
Min −4.4 44 −78 2 Inferior Occipital Gyrus BA19
Centroid −4.0 42 −76 4 Medial Occipital Gyrus BA19

(E) LV1{CON and CNR1 TT}, Cluster 2 (Voxels = 82)
Max −3.0 −46 −48 6 Superior Temporal Gyrus BA39
Min −3.9 −50 −42 4 Medial Temporal Gyrus BA22
Centroid −3.1 −52 −40 6 Medial Temporal Gyrus BA22

(F) LV1{CON and CNR1 TT}, Cluster 3 (Voxels = 40)
Max −3.0 −46 −22 2 Superior Temporal Gyrus BA22
Min −3.6 −42 −16 0 Insula BA13
Centroid −3.1 −46 −20 2 Superior Temporal Gyrus BA22

(G) LV2{CON, increasing scores on the Perceived Stress Scale, and FAAH CC}, Cluster 1 (Voxels = 276)
Max 4.5 44 −16 6 Insula BA13
Min 3.0 52 −20 2 Superior Temporal Gyrus BA22
Centroid 4.5 44 −16 6 Insula BA13

(H) LV2{CON, increasing scores on the Perceived Stress Scale, and FAAH CC}, Cluster 2 (Voxels = 141)
Max 4.1 54 −60 6 Medial Temporal Gyrus BA37
Min 3.0 44 −58 8 Medial Temporal Gyrus BA39
Centroid 3.8 52 −58 6 Medial Temporal Gyrus BA37

(I) LV2{CON, increasing scores on the Perceived Stress Scale, and FAAH CC}, Cluster 3 (Voxels = 83)
Max 3.7 4 −72 18 Cuneus BA18
Min 3.0 8 −74 18 Cuneus BA18
Centroid 3.2 2 −72 20 Cuneus BA18

(J) LV2 {MJ and FAAH AA+AC}, Cluster 1 (Voxels = 23)
Max −3.0 −14 −68 38 Precuneus BA7
Min −3.5 −10 −68 38 Cuneus BA7
Centroid −2.9 −12 −66 40 Precuneus BA7

(K) LV2 {MJ and FAAH AA+AC}, Cluster 2 (Voxels = 19)
Max −3.0 −16 20 −6 Caudate Caudate Head
Min −3.4 −12 16 −4 Caudate Caudate Head
Centroid −3.1 −14 18 −2 Caudate Caudate Head

(L) LV2{MJ and FAAH AA+AC}, Cluster 3 (Voxels = 10)
Max −3.0 20 −98 10 Cuneus BA17
Min −3.3 18 −98 8 Cuneus BA17
Centroid −3.0 16 −96 8 Cuneus BA17