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. 2021 Apr 20;120(9):1846–1855. doi: 10.1016/j.bpj.2021.03.030

Table 2.

Thermodynamics of RILPL2 binding to pRab8a/Rab8TE

Kd (μM) ΔH (kcal/mol) −TΔS (cal/k•mol) N
Rab8TE(Q67L)

RL2129 3.4 ± 0.5 −2.7 ± 0.3 −4.6 ± 0.5 1.03 ± 0.05

pRab8a(Q67L)

RL2129 3.3 ± 0.4 −5.1 ± 0.4 −2.2 ± 0.4 0.92 ± 0.2
RL2117 0.54 ± 0.1 −7.4 ± 0.2 −1 ±0.3 1.1 ± 0.15
RL2-FL 1.4 ± 0.3 −1.4 ± 0.3 −6.4 ± 1.2 1.04 ± 0.1