Table 1.
Imaging techniques and contrast agents applied for the detection of woodchuck hepatocellular carcinoma
Imaging technique
|
Contrast agent
|
Brand name
|
Ref.
|
Ultrasonography | Air-filled albumin microspheres | [195] | |
Cyanacrylate polymer microparticles | SHU563A | [196] | |
Dodecafluoropentane emulsion | EchoGen | [197,198] | |
Galactose microparticles/palmitic acid | Levovist | [199-201] | |
Perflexane-filled lipid microspheres | Imagent | [202] | |
Perfluoropropane-filled albumin microspheres | Optison/FS069 | [95,200,201,203,204] | |
Scintigraphy | 99mTc-sulfur colloid | [205] | |
Positron-emission tomography | [1-11C]acetate | [206-208] | |
[1-14C]acetate | [207] | ||
[N-methyl-11C]choline | [206,209,210] | ||
[18F]clofarabine | [211] | ||
[18F]fluoro-ethylcholine | [210] | ||
Anti-1-amino-3-[18F]fluoro-cyclobutyl-1-carboxylic acid | [212] | ||
2-deoxy-2-[18F]fluoro-D-glucose | [208,209,213] | ||
6-deoxy-6[18F]fluoro-D-glucose | [206,209,210] | ||
L-[S-methyl-11C]methionine | [212] | ||
3-deoxy-3-[18F]fluoro-thymidine | [214] | ||
Magnetic resonance imaging | Gadolinium | Gadavist or Omniscan | [157,179,185] |
Gadopentetate dimeglumine | Magnevist | [158,189] | |
Iron oxide | [215,216] | ||
Computed tomography | Biodegradable radiopaque fiducial markers based on polymers and iodine | Ioversol, Isovue-370, Optiray300, or Optiray350 | [152,153,159,186,206] |
Diatrizoic acid | Angiografin | [190] | |
Meglumine iotroxate | Biliscopin | [151] | |
Iohexol | Omnipaque or Omnipaque350 | [157,188] |