Figure 1.

Sequence charge decoration matrices (SCDMs) reveal protein specific patterns facilitating functional classification. SCDMs are shown for LKCharge, PEX5, SCCharge, SC5A, and RAD26 (from left to right). The color coding above depicts where the contribution of electrostatics is predicted to be repulsive (red) or attractive (blue). A clear visual pattern of three repulsive clusters near the diagonal is seen to emerge in the functional linkers (LKCharge, PEX5, and SCCharge) that is not present in the nonfunctional linkers (SC5A and RAD26). To see this figure in color, go online.